
cell
function
The
shape depends on the adaptation to a particular function.
ways:
· Globular or spherical: it is the most common
· Starry: nerve cells (neurons) and bone cells
(osteocytes or osteoblasts)
· Fusiform: muscle cells (fibers)
· Polyhedron (prism): plant cell and epithelial cells
Cells with a variable: amoeba and leukocytes (amoeboid
movement to deform
move or capture food)
Cell Size
Usually between 5 and 60
Å = Armstrong = ten thousandth of a micron
Special
cases:
large:
· Acetabularia: unicellular algae of 10 cm.
· Muscle cells of some cetaceans: 15 cm.
· The egg of the Ostrich: 7-8 cm.
small:
· Mycoplasmas: prokaryotic cell type 1/10 micron
· Bacteria: 0'2 - 0'5?
· Number of cells
From 1 to unicellular organisms to multicellular any
amount in the
Eukaryotic Cell Structure Animal
· Wrap cell
- Membrane secretion:
Glycocalyx (glycocalyx, glycocalyx, glycocalyx) in
some animal cells
* Glycocalyx: Made oligosaccharides (glucidic parts of
glycoproteins (and glycolipids of the
plasma membrane
- Cell Wall in all plant cells
- Plasma membrane:
¨ Two layers:
à outer (fibrous)
internal à (amorphous)
Phosphates (bony shell form) Polysaccharides:
¨ Chitin (exoskeleton)
¨ Chondroitin (tissues)
· Plasma membrane:
Generally ¨ is 75 Å thick
organelles and diseases
Cell Organelles
Key parts of the cell
A cell is formed by a plasma membrane, cytoplasm and
nucleus.
Plasma Membrane: Structure consisting of a lipid
bilayer formed by phospholipids arranged next to each other, forming a fluid
layer with proteins inserted into this (integral proteins), peripheral proteins
(external and internal). The center of the membrane is hydrophobic and internal
and external ends are hydrophilic.
The cytoplasm: This consists of the cytosol (liquid
fraction of the cytoplasm surrounding the organelles and has a gelatinous
consistency as). The cytoplasm has a cytoskeleton, organelles and inclusions.
In the cytoplasm are dissolved proteins, sugars, minerals, hormones and
enzymes.
Cytoskeleton: Formed by filamentous protein fibers.
These structures are dynamic, constantly build and break down and give way to
the cells, and also allows movement of the organelles. This consists of
Microtubules (tubulin), intermediate filaments and microfilaments (actin).
Organelles:
a) rough
endoplasmic reticulum, RER network is a flat bags delimited by a membrane whose
roughness is due to the presence of ribosomes on its surface. Its function is
to receive therein the newly made protein and ribosomes pemite by folding them.
Normally
b) this organelle
is abundant in secretory cells.
b) Ribosomes: organelles are not membrane consisting
of two subunits of RNA and proteins. They can be found free or attached to the
RER. Its function is to synthesize proteins.
c) Smooth endoplasmic reticulum, REL: A network of
flattened sacs, such as the RER without ribosomes on its surface, which gives a
smooth, not rough. Its function is to synthesize lipids (cholesterol, steroids
and phospholipids). In the liver, its function is to detoxify the cell of drugs
and toxins.
d) Golgi apparatus: A stack of flattened cisterns
parallel. Located near the nucleus and is highly developed in seretoras cells.
Its functions are: to receive vesicles with proteins, sugars chemically modify,
store and distribute them to your specified sites (organelles, plasma membrane,
drainage, etc.)., Factories lysosomes participate in the construction of the
cell wall of plant cells and produce polysaccharides as mucus. The whole
process is done by budding of vesicles.
e) Lysosomes: are bounded by a membrane vesicles,
which contain large quantities of hydrolytic enzymes and whose optimum pH is
acidic. Acid pH due to a proton pump exists in the membrane. Its function is
intracellular digestion, digest endocytosed material, including bacteria and
viruses. Also involved in autophagy, ie surrounding the organelles aged in
large vacuoles and are hydrolysates. Autolysis involved in, ie, break
lysosomes, as in the tadpole's tail.
f) Peroxisomes: These are spherical vesicles
surrounded by membrane. Are organelles self replicate. Generates hydrogen
peroxide (peroxide), which is used by an enzyme (catalase) to oxidize various
substances. Also performed on 30 of the catabolism of fatty acids.
g) Mitochondria: organelles are involved in two
membranes. The inner membrane invaginates, forming folds called mitochondrial
cristae. Mitochondria have the shape and size of bacteria, possess their own
DNA and circular and divided independent of the cell
that contains them. Within the mitochondria cellular
respiration occurs (Krebs cycle, electron transport chain and oxidative
phosphorylation). Its ultimate goal is to synthesize ATP for the cell.
h) centriole: microtubule organizing center. This
structure forms the fibers of the cytoskeleton, cilia, flagella and the mitotic
spindle.
i) Plastid: An example is the chloroplast,
photosynthesis takes place. Has a double membrane, like the mitochondria and
the nucleus. The inner membrane is the thylakoid. The green color of
chloroplasts is because chlorophyll. Lesser extent are also the pigments
carotene and xanthophylls. Other chromoplasts are plastids that accumulate
lipid pigment colors, leucoplasts and amyloplasts to store starch.
j) Cell wall: Around the membrane plant is a cell wall
made of cellulose and pectin. This cell wall substances passes freely passing
through the membranes. Its function is to prevent the burst due to accumulation
of cell water.
k) Vacuoles: spherical fluid-filled compartments in
plants. Is very large and contains water, nutrients, wastes, ions and salts. It
can give an osmotic pressure to allow the entry of water into the plant cell.
Inside may also have crystals, pegmentos (anthocyanins are blue and red ranges)
and tannins (brown give), alkaloids (cocaine, caffeine, protein, nicotine,
quinine, strychnine, mescaline, boldine and active compound
tetrahydrocannabinol marijuana) and terpenes (with herbs like mint and
eucalyptus and many flowers).
mitochondrial cytopathies
Mitochondriopathies are many and various diseases with
a common origin. All of which are caused by the alteration of some of the cells
mitochondria. These organelles, or organelles, are inside, in the same way that
the organs in the human body and have an important role in living organisms.
Mitochondria are the "factory" of energy in cells and in charge of
your breathing.
Because of the importance of exercising the functions,
are involved in many diseases and biological processes such as aging. Thus, it
is essential to know how they work and what implications in various
pathologies. Neither mitochondria nor mitochondrial damage should be outside
the knowledge of the general population, since the involvement of these
diseases has been linked as well known as Alzheimer's and Parkinson's, or other
minorities such as Huntington Korea.
Each body cell has hundreds of mtDNA molecules.
Dividing the cell to form daughter cells, this altered DNA is distributed
randomly. The result is the appearance of numerous and very different diseases,
which may be caused by abnormalities in the mitochondria. Although each tissue
characterized by different abilities to remove defective organelles,
some
are damaged for various reasons, such as oxidative stress and accumulation of
calcium.
pathogenic organisms

Pathogens, including viruses, bacteria or cysts, capable of causing
disease (typhus, cholera, dysentery) in a receiver (eg a person). There are
different types of organisms that cause disease NO. These are called non-pathogenic.
Regards
host specificity
In biology, host
means "hosting", ie, a guest is an organization that hosts a parasite
or symbiont. A host organism can become or be more likely to be by:
Genetic factors.

Age.
Physiological
conditions.
Interurrentes diseases
or preexisting.
BEHAVIOR or
lifestyle: One of the most important factors for the acquisition of human or
animal disease and the qe else can intervene, as they can be changed through
education or prevention modificandociertas husbandry practices:
Personal hygiene.
Food handling.
Diet.
Exercise.
Leisure activities or
hobbies.
Contacts.
Consumption of toxic:
Snuff, alcohol and other drugs
Host resistance
The pathogenicity of the organism is restrained or
provided by the host immune resistance. The properly vaccinated against
smallpox are immune to this virus. This fact was discovered by Jenner in
England, when he noticed that milkmaids who had been affected by the smallpox
vaccine, a disease of cattle and was acquired by manipulating the udders of the
animals did not suffer the deadly smallpox. Moreover, in patients with AIDS,
whose virus decreases immunity, may have disease germs usually harmless. are
caused by viruses, bacteria, protozoa, fungi, some invertebrate pathogen are a
kind of parasite that attack the body
Virus

is a microscopic infectious agent
that can only multiply within the cells of other organisms. Viruses infect all
types of organisms, from animals and plants, to bacteria and archaea. Viruses
are too small to be observed with the aid of a microscope, so that they are
said to submicroscopic.
Viruses vary in shape from simple helical and
icosahedral to more complex structures. The evolutionary origin of viruses is
still uncertain, some might have evolved from plasmids (pieces of DNA that move
between cells), while others may have originated from bacteria. Moreover, from
the viewpoint of the evolution of other species, viruses are an important means
of horizontal gene transfer, which increases the diversity genética.9

Viruses spread in many different
ways and each virus has a different method of transmission. These methods are
the vectors of transmission, which are other organisms that passed between
carriers. Plant viruses often spread by insects that feed on the sap, including
aphids, while animal viruses are usually spread by blood-sucking insects.
Moreover, other viruses do not require vectors: the influenza virus
(rhinovirus) is spread through the air through sneezing and coughing and
norovirus are transmitted by the fecal-oral, or by hands, food and contaminated
water. Rotavirus is often spread by direct contact with infected children. HIV
is one of the many viruses that are transmitted by sexual contact or by
exposure to infected blood. The word comes from the Latin virus referring to
poison or any harmful substance, and was first used in English in 1392.
Virulent, from Latin virulentus (poisonous), dates from 1400. The mention of
"agent that causes infectious disease" was first used in 1728, before
the discovery of viruses by Dmitri Ivanovski in 1892. The adjective
"viral" in 1948. The term "virion" is also used to refer to
a single infectious virus particle. The plural is "viruses".

Human diseases
caused by virus, more commonly known, are polio, influenza, smallpox, measles,
yellow fever, encephalitis, mumps, trachoma, etc.. Currently it is believed
that some cancers are also of viral origin. Viral infections in general, can
not be treated with antibiotics without signing on, the interferon biological
product synthesized by the tissues invaded by a virus, is active against
infections caused by others.
The existing treatments against viral infections are
often not entirely satisfactory, since most drugs that destroy the virus also
affects cells which reproduce. Alpha-adamantanamine is used in some countries
to treat respiratory infections caused by influenza A and
isatin-beta-thiosemicarbazone, effective against smallpox. Certain substances
similar to precursors of nucleic acids may be useful against serious infections
by herpes.
A promising antiviral agent is interferon, which is a
non-toxic protein produced by some animal cells infected with viruses and may
protect against other cell types such infections. Currently we are studying the
effectiveness of this substance to fight cancer. Until recently, these studies
were limited by their limited availability, but new techniques of cloning the
genetic material, produce large amounts of this protein. In a few years will
know if the interferon is really effective as an antiviral agent.
The only effective way to prevent viral infections is
the use of vaccines. Vaccination against smallpox worldwide in the 1970s,
eradicated the disease. They have developed many vaccines against human viruses
and other animals. Among the people who have infections include measles,
rubella, polio and influenza. Immunization with a vaccine stimulates antiviral
body's immune mechanism, which produces antibodies that will protect you when
you return to contact with the virus. Vaccines contain viruses forever altered
so they can not cause disease
Bacteria
Bacteria are
unicellular microorganisms that have a size of few micrometers (0.5 to 5
microns, usually) and various shapes including spheres (cocci), rods (bacilli)
and helices (spirilla). Bacteria are prokaryotes and therefore, unlike
eukaryotic cells (animals, plants, fungi, etc.) Have no defined or core have
generally membranous organelles internally. Generally possess a cell wall
composed of peptidoglycan. Many bacteria have flagella or other displacement systems
and are mobile. The study of bacteria is responsible for bacteriology, a branch
of microbiology.
Bacteria are the most
abundant organisms on the planet. Are ubiquitous, found in
all terrestrial and aquatic habitats, growing up in the most extreme as
in the hot springs and acidic wastes, radioactive, 1 in both the sea depths of
the earth's crust. Some bacteria can even survive in extreme conditions of
outer space. Is estimated to be found around 40 million bacterial cells in a
gram of soil and a million bacterial
cells in a milliliter of fresh
water. In total, it is estimated that approximately 5 × 1030 bacteria in the
world
In the human body are approximately ten times as many
bacterial cells as human cells, with a large amount of bacteria on the skin and
in the tract digestivo.4 Although the protective effect of the immune system
makes the vast majority of these bacteria is innocuous or beneficial some
pathogenic bacteria can cause infectious diseases, including cholera, syphilis,
leprosy, typhus, diphtheria, scarlet fever, etc.. The most common fatal
bacterial diseases are respiratory infections, with mortality for tuberculosis
only about two million people a year
The first bacteria were observed by Anton van
Leeuwenhoek in 1683 using a single lens microscope of his own design. Initially
called animalículos and published his observations in a series of letters to
the Royal Society. The name bacterium was introduced later in 1828 by
Ehrenberg. Derived from the Greek βακτήριον-α, Bacterion-a, which means small
stick.
A breakthrough in the study of bacteria was the
discovery by Carl Woese in 1977 that the archaea have a storyline different
from bacteria. This new phylogenetic taxonomy was based on the 16S ribosomal
RNA sequencing and divided the prokaryotes into two different evolutionary
groups, in a system of three domains: Archaea, Bacteria and Eukarya
Protozoa
Protozoa, also called protozoa, are microscopic,
unicellular Eukarya, heterotrophic fagótrofos, predators or | detritivores]],
sometimes mixotrophs (partly autotrophic) living in damp or directly in aquatic
environments, whether salt water or water sweet, asexual reproduction by
bipartition can be sexual also isogametos or exchanging genetic material by
conjugation. In this very diverse group taxa fit a remote kinship, which fall
into many different phyla of the kingdom Protista, defining a polyphyletic
group, with no value in the classification according to current criteria.
Characteristics
Protozoa generally range from 10-50 microns, but can grow
up to 1 millimeter, and can easily be viewed through a microscope. They move
with a whip-like tails called flagella. They are the family of the protist.
Found about 30,000 different types. Protozoans exist in aqueous environments
and soil, occupying a range of trophic levels. As predators, prey algae,
bacteria, unicellular or filamentous and microfungi. Protozoa play a role as
herbivores and as consumers in the coupling of the decomposition process of the
food
chain.Classification
Rhizopods or Sarcodina (Rhizopoda). Protozoa such as
amoebae, move through linkers, ie, forming temporary appendages from its
surface and a projection of the cytoplasm. The linkers are deformations of the
cytoplasm and plasma membrane that occur in the displacement direction and
trailing behind the rest of the cell. The pseudopods are also used to capture
food, which fall into the interior, in a process called phagocytosis. According
to the pseudopodia are very thick or very thin, are of two types: with
lobopodios (thick) as Lobosea (Amoebozoa) and filopodia usually accompanied by
a variety of exoskeleton with microtubules and are such as radiolarians,
foraminifera, nuclearias, heliozoa and other .
Ciliates (Ciliophora). This is the traditional group
most closely identified as a natural group
in the rankings with more modern edge, although they are cromistas
opalinatas also fit into this concept. Cilia
are surrounded by and have a complex internal
structure but similar to the flagella, which are also related to cytoskeleton and
centrioles. The paramecium (Paramecium genus) is a very popular representative
of the group. Furthermore, the cilia are very numerous short filaments and that
with its movement causes displacement of the cell. Flagellates or mastigophores (Mastigophora). They are
distinguished by the possession of one or more flagella. The flagella filaments
are longer than the cilia whose movement drives the cell. Often occur in small
numbers. The unicellular naked (cell wall), equipped with only one or two
flagella, represent the original form from which derive all eukaryotes. Why are
so many and varied different protists that fit this concept. Plants for example
derived ancestrally biflagellate protozoan that acquired plastids by
endosymbiosis with a cyanobacteria. Several protozoa carry plastids and are
therefore autotrophs or mixotrophs as dinoflagellates and euglenas. The
Metamonada have two or multiple flagella, are mostly anaerobic and symbionts or
parasites of animals. Among the uniflagelados are choanoflagellates, ancestral
animals and chytrids, ancestral fungi.
Sporozoa or Apicomplexa. Parasites with a phase of
sporulation (division multiplex) and without mobility. There are several
distinct groups without further relationship and are not all protists, but no
animals and fungi. The best known example is the protozoan parasite (genus
Plasmodium) that causes malaria and belongs to the group of apicomplexan,
best-known group that usually reserved for himself the name Sporozoa. The
haplosporidians are considered part of Cercozoa. These two groups were brought
together for a long time under the name of Cnidosporidios. The Ichthiosporea
are a more recent and are within Choanozoa. Microsporidia are now assigned to
the kingdom Fungi and mixosporidias or mixozoos the animal kingdom.
fungal infections
designates a group of eukaryotic organisms that are
among the molds, yeasts and mushrooms. They are classified into a different
realm of plants, animals and bacteria. This differentiation is due, inter alia,
that possess cell wall composed of chitin, unlike plants, containing cellulose
and because some grow and / or act as parasites of other species. Currently
considered as a heterogeneous group, polyphyletic, consisting of bodies
belonging to at least three independent storylines.
Fungi are found in diverse habitats: be pirófilos
(Pholiota carbonaria) or coprophilous (Psilocybe coprophila). According to
their ecology, can be classified into four groups: saprophytes, lichenized,
mycorrhizal and parasites.

Fungi are of great economic importance: yeasts are
responsible for the fermentation of beer and bread, and gives the collection
and cultivation of mushrooms and truffles. Since 1940 have been used
industrially to produce antibiotics and enzymes (especially proteases). Some species
are biocontrol agents of pests. Others produce mycotoxins, bioactive compounds
(eg alkaloids) that are toxic to humans and other animals. Fungal diseases
affecting humans, animals and plants in the latter affects the food security
and crop yields.
Fungi come in two main forms: filamentous fungi
(formerly called "molds") and yeast.
commonalities
Other eukaryotic cells fungi possess bounded by a
sterol-rich plasma membrane and containing a core which contains the genetic
material in the form of chromosomes. This genetic material contains genes and
other coding and noncoding elements such as introns. Possess organelles such as
mitochondria, and ribosomes 80S.8 As such compounds possess soluble
carbohydrate reserves and polyalcohols (eg mannitol), disaccharides (such as
trehalose) and polysaccharides (such as glycogen, which, moreover, is present
in animals)
As animals, fungi lack chloroplasts. This is due to
their heterotrophic nature, requiring obtained as a carbon source, energy and
reducing power organic compounds
to like plants, fungi have cell walls and vacuoles.
They reproduce in a sexual and asexual, and, like ferns and mosses produce
spores. Because of their life cycle, usually possess haploid nuclei, as mosses
and algae. Bear resemblance to fungi and bacteria euglenoid.
multicellular parasites

These are the major multicellular
parasites of the intestine; Hookworms (Ancylostorna duodenale). Worms are about
3 mm long, fitted with hooks that oral are fixed to the wall of the duodenum,
where they suck the blood of the wearer. If the infestation (hookworm) is
severe, manifested by chronic anemia, abdominal pain and weight loss. The
larvae can reach the intestine directly penetrate the mouth or skin wounds and
travel through the blood to the lungs, where they pass into the throat and are swallowed.
Roundworm (Ascaris lunsbricoides). They are pinkish-white worms, up to 30 cm
long. The infestation (ascariasis), common among children in unhealthy regions,
occurs when you take food or water contaminated with human feces containing the
eggs, its symptoms include bloating, malnutrition, growth retardation and the
presence of worms in the stool. Pinworms (Enterobius vermicularis). are worms Whites
from 3 to 12 mm long that infest the large intestine (oxiurasis). During sleep,
females down to the anus, in whose folds lay their eggs, causing intense
itching. If the person scratches, the eggs are stuck to the nails, making them
easier to spread. The eggs also stick to the bedding, where their ability to
infestation may last for several weeks. The oxiurasis occurs even under the
best conditions hygiene, particularly among children 3 to 15 years of age.
Tapeworms. Are flatworms, up to 10 m length, which are fixed with suckers or
hooks to the gut wall. There are two main species, the solitary or pork
tapeworm (Taenia solium) and the beef tapeworm (Taenia saginata).

Infestation (taeniasis) is caused by eating raw or
undercooked meat of cattle parasitized, can be asymptomatic, but sometimes
causes abdominal pain, diarrhea, anemia or weight loss. Naturopathic advice is
said that garlic, carrot and pumpkin seeds serve to weaken various parasitic
worms, but you also have potent plant remedies used to paralyze and expel them,
which calls for consultation with a therapist












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